It was invented in 1946 by Diego Zamora, along with his brother and sister, Angel and Josefina Zamora, and Emilio Restoi, Josefina's husband. Licor 43 was based on their recipe for Liqvor Mirabilis, a golden, aromatic liqueur produced and infused from local fruits and herbs in Carthago Nova during the 3rd century. Liqvor Mirabilis was encountered by the Romans when they conquered the area in 209 BC. despite the fact that the Romans banned its production and consumption, the Carthaginians continued to produce secretly. This legend served as inspiration for Zamora's invention of Licor 43. The name of the modern liqueur comes from the use of 43 different ingredients. While its recipe is a well-kept secret from the Zamora family, it is known to contain citrus and fruit juices and to be flavored with vanilla, among other aromatic herbs and spices.